This site has limited support for your browser. We recommend switching to Edge, Chrome, Safari, or Firefox.

Use coupon code WELCOME10 for 10% off your first order.

Cart 0

Congratulations! Your order qualifies for free shipping You are $300.00 AUD away from free shipping.
No more products available for purchase

Pair with
Add order notes
Is this a gift?
Subtotal Free
Shipping, taxes, and discount codes are calculated at checkout

Maximising Muscle Health: EP-11® the Myostatin Inhibitor

Written by: APOC Science Team



Time to read 11 min

Myostatin and Follistatin: Myostatin and follistatin have been classified as autocrine muscle peptide hormones

Myostatin and Follistatin Role: Myostatin limits muscle growth, while follistatin promotes it by blocking myostatin

Muscle Regulation and Adaptation : Muscles produce myostatin and follistatin, regulating themselves through feedback, essential for strengthening and resilience.

EP-11® Supplement : Developed by APOC Science®, EP-11® boosts muscle function by adjusting myostatin and follistatin levels, supporting growth and repair.

Agieng and Muscle Health : Aging causes muscle mass decline due to myostatin-follistatin axis imbalances. EP-11® targets these changes to improve muscle health.

Nutritional Support : Nutrition is key for muscle health; EP-11® adds to this by providing extra muscle support and recovery aid.

Future of Muscle Health : Ongoing research into muscle function and treatments like EP-11® shows promise for significantly better muscle health.

Our Allied Health Professionals have developed a short quiz to assess if you'd benefit from our Muscular Support Supplement. Take the Muscular Function Quiz here.

Introduction: Unlocking the Secrets of Muscle Health

Welcome to our exploration of muscle health! Come with us as we delve into the fascinating world of myostatin and follistatin. These two muscle peptide hormones play a crucial role in regulating muscle growth and development in the human body.

Myostatin is a peptide hormone that stops muscles from growing and multiplying. In other words, high levels of myostatin can limit muscle growth and lead to decreased muscle mass. Another peptide hormones called follistatin, blocks myostatin and in doing so promotes muscle development.

Understanding the balance between myostatin and follistatin is essential for maintaining optimal muscle health. Studying how these peptide hormones work together and impact muscle growth can help us improve muscle health.

We can improve our muscle health by learning about how natural peptide hormones affect muscle growth. Making the right choices in food, exercise, and lifestyle can lead to improved muscle health.

Join us as we explore how to keep your muscles healthy. Discover the impact of myostatin and follistatin on muscle fibers.

At APOC Science® we have a mission to study how to make muscles work better. Our EP-11® supplement is a breakthrough product that helps improve muscle function. EP-11® is our innovation, designed to empower you on your quest for optimal muscle function.

Decoding Autocrine Mucle Peptide Hormones: What They Mean for You

Myostatin and follistatin are a powerful duo in the world of muscles. Each one has a unique role in controlling the growth and progress of your muscles.

Myostatin regulates muscle growth by stunting it, while follistatin regulates muscle growth by promoting it. Both work together to maintain muscle balance and function. Picture them as a music duo – myostatin as the stern conductor and follistatin as the creative composer.

Just like in a music group, myostatin takes on the role of the tough leader, setting strict guidelines and boundaries for muscle growth. Like the conductor, ensuring that muscles follow a disciplined path and don't grow too large or out of control. Myostatin inhibits muscle cell proliferation and differentiation, keeping muscles in check and preventing them from overgrowing.

On the flip side, follistatin steps in as the leader in promoting muscle growth. Like the composer, it's all about creativity and encouragement. Follistatin blocks myostatin, promoting muscle growth and repair to reach full potential and thrive.

Myostatin and follistatin work together like a symphony, perfectly harmonising to regulate muscle growth and function. But here's the fascinating part: your muscles themselves produce these hormones, a process known as autocrine myoregulation – the regulation of muscles.

Autocrine refers to a substance that acts on the cells that produce it. For example, muscles produce myostatin and follistatin, which then act back on the muscles that produced them. This creates a complex feedback loop.

Hormone indicates their role in sending signals to regulate bodily functions, specifically muscle growth and repair. Myostatin and follistatin are like internal messengers that tell muscle cells how to grow and develop properly.

Your muscles can change and respond to exercise and injury. This is similar to how a musician adjusts to different music. The balance of myostatin and follistatin levels plays a role in this process. This delicate dance helps maintain optimal muscle function and performance, allowing you to move, lift, and thrive.

Follistatin: The Myostatin Blocker

Follistatin reduces myostatin levels through a complex mechanism involving competitive binding and inhibition. Myostatin and follistatin are natural antagonists in the body, meaning they have opposite effects on muscle growth regulation. Myostatin acts as a negative regulator, limiting muscle growth, while follistatin acts as a positive regulator, promoting muscle growth.

When follistatin is present in the body, it competes with myostatin for binding sites on muscle cells. Follistatin stops myostatin from causing muscle growth problems by blocking its interaction with receptors. This competition between follistatin and myostatin ultimately results in reduced myostatin activity and levels in the muscle tissue.

Follistatin keeps muscles healthy and working well. This happens even when there is a lot of myostatin present. The interaction between follistatin and myostatin is important for regulating muscle growth in the body.

Myostatin and Follistatin: The Dynamic Duo of Muscle Regulation

Myostatin and follistatin are like the yin and yang of muscle regulation. They work together to keep muscle growth and repair in balance.

Myostatin acts as a brake, preventing muscles from growing too large and potentially causing damage to surrounding tissues. On the other hand, follistatin acts as an accelerator, promoting muscle growth and repair. Together, these two molecules ensure that your muscles stay strong, functional, and resilient.

Understanding the Myostatin-Follistatin Axis: Your Body's Muscle Health Barometer

The myostatin-follistatin axis is important for muscle health. The levels of myostatin and follistatin in your body indicate the condition of your muscles.

As we age, our bodies can disrupt this balance, causing a decline in muscle mass, strength, and function. As people age, they may experience muscle challenges like age-related sarcopenia.

An imbalance in the body often causes these challenges. This imbalance shows lower levels of follistatin and higher levels of myostatin. EP-11® helps balance the body by reducing myostatin and increasing follistatin levels, which improves muscle function.

The Benefits of Myostatin and Follistatin in Muscle Health

Myostatin is an autocrine peptide hormone that prevents muscles from becoming excessively hypertrophied. This is important because overly bulky muscles can put strain on the body and increase the risk of injury. Myostatin keeps muscles strong and healthy by preventing them from growing excessively large.

On the other hand, follistatin is an autocrine peptide hormone that promotes muscle growth, repair, and regeneration. It works by blocking the activity of myostatin, allowing muscles to grow and repair more effectively. Follistatin is important for maintaining muscle health by increasing muscle mass, strength, and endurance.

Together, myostatin and follistatin play complementary roles in regulating muscle growth and function. Myostatin helps to prevent muscles from becoming too bulky, while follistatin promotes muscle growth and repair. By working together, these proteins help to ensure that muscles are strong, resilient, and able to perform at their best. By modulating the levels of these two molecules, EP-11® helps optimise muscle health and performance.

The Impact of Ageing on Muscle Health

Muscle loss is a common condition that affects many individuals as they age. As we age, our muscles can undergo a condition called age-related sarcopenia, a type of muscle atrophy. This results in our muscles becoming smaller, weaker, and less effective over time, impacting our overall health and quality of life.

One of the key factors contributing to age-related sarcopenia is changes in our myostatin and follistatin hormone levels. As we get older, our bodies start producing imbalanced levels of these important autocrine peptide hormones. These hormones are essential for keeping our muscles strong and maintaining muscle mass. This hormonal imbalance can lead to a loss of muscle tissue and a decline in muscle function over time.

In addition to hormonal changes, decreased physical activity is another important factor in the development of age-related sarcopenia. As people age, they tend to become less active, leading to a loss of muscle mass and strength.

This can create a harmful cycle. Decreased muscle mass can lead to less physical activity. This can make muscle function decline even more.

Alterations in muscle metabolism also play a role in the development of age-related sarcopenia. As we age, our bodies struggle to produce and repair muscle tissue. This leads to a decline in muscle mass and strength over time.

This can get worse because of things like not eating well, being sick for a long time, and taking medication. These things can affect how muscles work and make age-related sarcopenia worse.

Age-related sarcopenia is a complex condition. Various factors such as hormonal changes, decreased physical activity, and alterations in muscle function influence it.

Hormonal changes can play a role in the development of age-related sarcopenia. Reduced physical activity can also contribute to the condition. Changes in how muscles work can further impact the progression of age-related sarcopenia.

To prevent muscle loss, weakness, and decreased function that occur with age, people can take steps to address these factors. Understanding the causes and implementing strategies can slow or reverse the decline. To stay strong and healthy as you age, make proactive lifestyle changes to maintain muscle mass and strength.

One important factor is the imbalance between muscle growth and breakdown caused by dysregulation of the myostatin-follistatin axis. EP-11® helps maintain muscle health and function as you age by balancing myostatin and follistatin levels.

The Science of Muscle Adaptation

When we go to the gym or lift weights, our muscles adapt to the stress like a superhero, making us stronger. When we challenge our muscles with exercise, they don't back down. Instead, they kick into high gear, triggering a series of molecular events that lead to growth and resilience.

Picture this: during resistance exercise, our muscles work harder than usual. They push to the limit, causing tiny tears in the muscle fibres.

But here's the magic – our body doesn't panic. Instead, it springs into action, activating special cells called satellite cells. These little helpers rush in to repair and build new muscle tissue, making our muscles stronger and more durable.

As our muscles repair and rebuild, they level up. They become better equipped to handle stress and push through tough workouts. With consistent training and proper recovery, our muscles continue to adapt and grow in both size and strength.

Muscle adaptation isn't just a fancy term – it's the secret sauce to improving our physical fitness and performance. Whether we're pumping iron or doing body-weight exercises, our muscles thrive on challenge. That's why it's important to change our workouts, mixing up how hard we exercise and the kind of training we do. This helps our muscles stay challenged and get stronger.

But it gets even better when we add EP-11® to our training routine, it can boost our muscle adaptation. EP-11® enhances the adaptive response of our muscles, leading to greater gains in strength, size, and function. So, if you're ready to take your workouts to the next level, give EP-11® a try and watch your muscles soar!

The Importance of Nutritional Support

To keep your muscles healthy in the long term, it's important to exercise, take supplements, and eat well. Think of it as the fuel that powers your muscle machine. In nutrition, balance is key.

First up, protein: the building blocks for your muscles. Eating enough protein ensures that your muscles have the raw materials they need to grow and repair after a tough workout. Carbohydrates are important for providing energy to your muscles during exercise.

Then we have healthy fats, vitamins, and minerals as also essential for muscle metabolism and overall health. They keep your muscles functioning smoothly and support your body's internal processes.

EP-11® improves your diet by providing important nutrients and compounds that support muscle health and function. Giving your muscles an extra boost is like ensuring that they have everything they need to thrive.

So, whether you're hitting the gym or simply trying to stay active, don't forget about the power of nutrition. Fuel your body with the right nutrients and add EP-11® to supercharge your muscle health and reach your fitness goals faster.

EP-11®: A Holistic Approach to Muscle Optimisation

EP-11® is not like other muscle supplements. It focuses on improving muscle health by addressing various factors that impact muscular function. EP-11® supports your muscles from the inside out with its special mix of nutrients and bioactive compounds.

EP-11® has a key superpower: it can regulate myostatin and follistatin levels, which are essential for muscle regulation. By keeping these two in check, EP-11® ensures that your muscles can grow and repair effectively, without any pesky roadblocks getting in the way.

But wait, there's more! EP-11® not only supports muscle metabolism, but also provides the energy necessary for your muscles to push through challenging workouts. Plus, it aids in recovery, helping you bounce back faster after intense exercise sessions.

In essence, EP-11® is a one-stop solution for anyone looking to improve their muscle health. EP-11® helps muscles grow and repair by targeting multiple pathways. This makes it useful for anyone working towards their fitness goals. So if you're ready to take your muscle health to the next level, give EP-11® a try and experience the difference for yourself.

The Future of Muscle Health: Innovations and Advances

Scientists are discovering new information about muscle health. They've gone from researching the bioactive of EP-11® in adult mice, to comprehensive clinical trials in humans.

This new information is changing our understanding of how muscles work. Also helping us learn how to improve muscle health. New technologies such as advanced cameras, genetic manipulation, and biomechanical studies are aiding scientists in understanding muscle function.

These tools provide valuable insights into the workings of muscles. Cameras capture detailed images of muscle movements. Genetic studies reveal how genes influence muscle development and function. Biomechanical research examines how the body moves and how muscles contribute to movement.

Researchers are finding new ways to enhance muscle strength and performance. One method involves using the bioactive ingredient in EP-11® to treat muscular dystrophy. This is in addition to advancements in technology.

From innovative drug therapies to personalised exercise regimens, the possibilities for improving muscle health are expanding rapidly.

Scientists are studying different ways to help people improve their muscle function. They are looking into gene therapy, stem cell treatments, and specific exercise programs.

Conclusion: Embracing a Future of Optimal Muscle Health with Our Myostatin Inhibitor

In conclusion, EP-11® represents a paradigm shift in the way we approach muscle health and ageing. EP-11® - our myostatin inhibitor - helps muscles grow, repair, and regenerate by balancing myostatin and follistatin levels. With its holistic approach, proven efficacy, and commitment to scientific excellence, EP-11® empowers individuals to embrace a future of optimal muscle health and vitality.

Ready to take the next step in your journey to optimal muscle health? Visit our EP-11® Product Page and start your journey today.


[1] Temirgaziyev BS, Kucakova K, Baizhigit YA, Jurasek M, Dzubak P, Hajduch M, et al. Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins. Steroids. 2019;147:37-41. DOI: 10.1016/j.steroids.2018.11.007

[2] Wang L, Li S, Cai H, Liu X, Feng T, Zhao X. Preparation and characterisation of ecdysterone/hydroxypropyl-Beta-cyclodextrin inclusion complex with enhanced oral and transdermal bioavailability. J Microencapsul. 2022;39(2):145-55. DOI: 10.1080/02652048.2022.2056251

Leave a comment